The Peptide Observer

Peptide research, explained for people who are not scientists.

Quick answer

What is TB-500?

Built from index records dated 2026-10-09 to 2026-10-13 Compiled by an automated pipeline, checked by The Peptide Observer editorial desk How this site works

TB-500 is a peptide, grouped on this site under Tissue repair peptides, and the 12 research records kept here are 2 from studies in rats or mice and 10 that do not state what kind of study it is.

The literature search returned 30 records. This site keeps 12 of them, which is 40 per cent of what came back.

What it is

This site puts it in the Tissue repair peptides group.

A synthetic fragment of thymosin beta 4; the retrieved records characterise the material rather than report a mechanism of its own, so the actin-sequestering mechanism belongs to the parent peptide.[1, 2]

Stated in the titles of the cited 2012 Journal of Chromatography A and 2012 Drug Testing and Analysis papers.

What kind of records

The records kept here are animal and laboratory studies only.

That sentence is produced by counting, not by reading. What was counted: no interventional human trial record; 2 rodent and 0 in vitro records among 12.

What this does not settle

Where this comes from

The records cited above, in full.

  1. Doping control analysis of TB-500, a synthetic version of an active region of thymosin β₄, in equine urine and plasma by liquid chromatography-mass spectrometry. Journal of chromatography. A (2012). pmid:23084823
  2. Synthesis and characterization of the N-terminal acetylated 17-23 fragment of thymosin beta 4 identified in TB-500, a product suspected to possess doping potential. Drug testing and analysis (2012). pmid:22962027