Quick answer
What is Melanotan II?
Built from index records dated 2026-10-09 to 2026-10-13 Compiled by an automated pipeline, checked by The Peptide Observer editorial desk How this site works
Melanotan II is a peptide, grouped on this site under Melanocortin receptor peptides, and the 12 research records kept here are 9 from studies in rats or mice and 3 that do not state what kind of study it is.
The literature search returned 199 records. This site keeps 12 of them, which is 6.0 per cent of what came back.
What it is
This site puts it in the Melanocortin receptor peptides group.
A cyclic melanotropic peptide acting as a melanocortin receptor agonist; the retrieved literature describes it as non-selective across melanocortin receptor subtypes relative to the pigment-selective analogues.[1, 2, 3] (derived value: Derived: the cited 1996 Life Sciences and 2000 International Journal of Impotence Research titles establish melanotropic and melanocortin receptor agonist activity. The relative-selectivity clause is derived from the contrast between those reports and the pigmentary indication of the cited afamelanotide trial, not stated in any one retrieved title.)
Derived: the cited 1996 Life Sciences and 2000 International Journal of Impotence Research titles establish melanotropic and melanocortin receptor agonist activity. The relative-selectivity clause is derived from the contrast between those reports and the pigmentary indication of the cited afamelanotide trial, not stated in any one retrieved title.
What kind of records
The records kept here are animal and laboratory studies only.
That sentence is produced by counting, not by reading. What was counted: no interventional human trial record; 9 rodent and 0 in vitro records among 12.
What this does not settle
- What it does in a body. Counting records is not reading them, and nothing here has been read in full.
- Whether it causes harm. No adverse-effect row was taken from any source for this entry.
- How long it lasts. No pharmacokinetics source was retrieved for this entry.
- What the other 187 retrieved records say. They are not in this index.
The longer explanation
Where this comes from
The records cited above, in full.
- Evaluation of melanotan-II, a superpotent cyclic melanotropic peptide in a pilot phase-I clinical study. Life Sci (1996). pmid:8637402
- Melanocortin receptor agonists, penile erection, and sexual motivation: human studies with Melanotan II. Int J Impot Res (2000). pmid:11035391
- Afamelanotide for Erythropoietic Protoporphyria. N Engl J Med (2015). pmid:26132941