Quick answer
What is Mechano growth factor?
Built from index records dated 2026-10-09 to 2026-10-13 Compiled by an automated pipeline, checked by The Peptide Observer editorial desk How this site works
Mechano growth factor is a peptide, grouped on this site under Growth factors and growth hormone-derived compounds, and the 12 research records kept here are 7 from studies in rats or mice and 5 that do not state what kind of study it is.
The literature search returned 222 records. This site keeps 12 of them, which is 5.4 per cent of what came back.
What it is
This site puts it in the Growth factors and growth hormone-derived compounds group.
An IGF-I splice variant whose E-domain peptide is reported in the retrieved records to act on muscle progenitor cells; the 2014 American Journal of Physiology record reports no apparent effect in its model, so the mechanism is contested in the retrieved set.[1, 2]
Stated in the titles of the cited 2011 Mechanisms of Ageing and Development and 2014 American Journal of Physiology papers.
What kind of records
No public chemistry record was found under this name, so the entry describes a preparation, a protein or a mixture rather than one defined molecule.
That sentence is produced by counting, not by reading. What was counted: PubChem returned no compound record for this name, so the subject is a preparation, protein or mixture rather than a defined small molecule; identity fields are unsourced.
What this does not settle
- What it does in a body. Counting records is not reading them, and nothing here has been read in full.
- Whether it causes harm. No adverse-effect row was taken from any source for this entry.
- How long it lasts. No pharmacokinetics source was retrieved for this entry.
- What the other 210 retrieved records say. They are not in this index.
The longer explanation
Where this comes from
The records cited above, in full.
- Mechano Growth Factor E peptide (MGF-E), derived from an isoform of IGF-1, activates human muscle progenitor cells and induces an increase in their fusion potential at different ages. Mechanisms of ageing and development (2011). pmid:21354439
- Mechano-growth factor peptide, the COOH terminus of unprocessed insulin-like growth factor 1, has no apparent effect on myoblasts or primary muscle stem cells. American journal of physiology. Endocrinology and metabolism (2014). pmid:24253050